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The American Society of Breast Surgeons.
Annals of Surgical Oncology

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Volume 26, Number 13 / December, 2019

ASO Author Reflections

ASO Author Reflections: A Negative Axillary Clinical Exam Adequately Identifies Clinically Node-Positive Patients who Downstage After NAC and are Candidates for SLNB

Tracy-Ann Moo MD, Monica Morrow MD
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ASO Author Reflections: Should Breast Density Influence Patient Selection for Breast-Conserving Surgery?

Siun M. Walsh MD, Mary L. Gemignani MD, MPH
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ASO Author Reflections: Advising a Woman with Ductal Carcinoma In Situ Regarding Various Treatment Options—A Complex Decision

Anita Mamtani MD, Kimberly J. Van Zee MS, MD
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ASO Author Reflections: What Role Do Surgeons Play in the Era of Effective Systemic Therapy for Melanoma?

Daniel W. Nelson DO, Mark B. Faries MD
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ASO Author Reflections: Survival for Stage III Melanoma—Where Do We Stand in the Current Landscape of Melanoma Therapies?

Yun Song MD, Giorgos C. Karakousis MD
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Breast Oncology

Flipping a Coin? Predicting Nodal Status After Neoadjuvant Chemotherapy

Theresa Schwartz MD, MS, FACS, Julie Margenthaler MD, FACS
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Is Clinical Exam of the Axilla Sufficient to Select Node-Positive Patients Who Downstage After NAC for SLNB? A Comparison of the Accuracy of Clinical Exam Versus MRI

Tracy-Ann Moo MD, Maxine S. Jochelson MD, Emily C. Zabor DrPH, Michelle Stempel MPH, Monica Raiss BA, Anita Mamtani MD, Audree B. Tadros MD, Mahmoud El-Tamer MD, Monica Morrow MD
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Does Breast Density Increase the Risk of Re-excision for Women with Breast Cancer Having Breast-Conservation Therapy?

Siun M. Walsh MD, Sandra B. Brennan MD, Emily C. Zabor DrPH, Laura H. Rosenberger MD, Michelle Stempel MPH, Lizza Lebron-Zapata MD, Mary L. Gemignani MD, MPH
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Circumferential Shaving of the Cavity in Breast-Conserving Surgery: A Randomized Controlled Trial

Kai Chen MD, Liling Zhu MD, Lili Chen MSN, Qian Li BSN, Shunrong Li MD, Na Qiu AST, Yaping Yang MD, Fengxi Su MD, Erwei Song MD, PhD
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Impact of Age on Locoregional and Distant Recurrence After Mastectomy for Ductal Carcinoma In Situ With or Without Microinvasion

Anita Mamtani MD, Faina Nakhlis MD, Stephanie Downs-Canner MD, Emily C. Zabor DrPH, Monica Morrow MD, Tari A. King MD, Kimberly J. Van Zee MS, MD
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Validation of Residual Cancer Burden as Prognostic Factor for Breast Cancer Patients After Neoadjuvant Therapy

Hannah Deborah Müller MD, Florian Posch MD, Christoph Suppan MD, Ute Bargfrieder MD, Melanie Gumpoldsberger MD, Robert Hammer MD, Hubert Hauser MD, Nadia Dandachi PhD, Kurt Prein MD, Herbert Stoeger MD, Sigurd Lax MD, Marija Balic MD, PhD
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Oncoplastic Central Partial Mastectomy and Neoareolar Reduction Mammoplasty with Immediate Nipple Reconstruction: An Initial Report of a Novel Option for Breast Conservation in Patients with Subareolar Tumors

Angelena Crown MD, Flavio G. Rocha MD, FACS, Janie W. Grumley MD, FACS
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Redefining Eligibility by Analyzing Canceled Intraoperative Radiotherapy as a Boost for Patients Undergoing Breast-Conserving Treatment

Jun Won Kim MD, PhD, Yeona Cho MD, Jinhyun Choi MD, Sung Gwe Ahn MD, Joon Jeong MD, PhD, Ik Jae Lee MD, PhD
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A Nomogram to Predict Factors Associated with Lymph Node Metastasis in Ductal Carcinoma In Situ with Microinvasion

Jessica C. Gooch MD, Freya Schnabel MD, FACS, Jennifer Chun MPH, Elizabeth Pirraglia MA, Andrea B. Troxel ScD, Amber Guth MD, FACS, Richard Shapiro MD, FACS, Deborah Axelrod MD, FACS, Daniel Roses MD, FACS
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Breast Cancer Found Incidentally After Reduction Mammaplasty in Young Insured Women

Kara Vande Walle MD, Dou-Yan Y. Yang PhD, Trista J. Stankowski-Drengler MD, Devon Livingston-Rosanoff MD, PhD, Sara Fernandes-Taylor PhD, Jessica R. Schumacher PhD, Lee G. Wilke MD, Caprice C. Greenberg MD, MPH, Heather B. Neuman MD, MS
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Risk of Contralateral Breast Cancer in Women with Ductal Carcinoma In Situ Associated with Synchronous Ipsilateral Lobular Carcinoma In Situ

Megan E. Miller MD, Shirin Muhsen MD, Emily C. Zabor DrPH, Jessica Flynn BS, Cristina Olcese BS, Dilip Giri MD, Kimberly J. Van Zee MS, MD, FACS, Melissa Pilewskie MD, FACS
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Patterns of Axillary Management in Stages 2 and 3 Hormone Receptor-Positive Breast Cancer by Initial Treatment Approach

Anna Weiss MD, Stephanie Wong MD, MPH, Mehra Golshan MD, Rachel A. Freedman MD, MPH, Otto Metzger MD, Jennifer Bellon MD, Elizabeth A. Mittendorf MD, PhD, Tari A. King MD
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Axillary Lymph Node Ultrasound Following Neoadjuvant Chemotherapy in Biopsy-Proven Node-Positive Breast Cancer: Results from the SN FNAC Study

Dominique Morency MD, MSc, FRCSC, Sinziana Dumitra MD, MSc, FRCSC, Elena Parvez MD, MSc, FRCSC, Karyne Martel MD, FRCSC, Mark Basik MD, MSc, FRCSC, André Robidoux MD, FRCSC, Brigitte Poirier MD, FRCSC, Claire M. B. Holloway MD, PhD, FRCPC, Louis Gaboury MD, PhD, FRCPC, Lucas Sideris MD, FRCSC, Sarkis Meterissian MD, FRCSC, Jean-François Boileau MD, MSc, FRCSC
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Trends in Regional Nodal Management of Breast Cancer Patients with Low Nodal Burden

Benjamin M. Raber MD, Heather Lin MS, PhD, Yu Shen BS, MS, PhD, Simona F. Shaitelman MD, Isabelle Bedrosian MD
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Impact of Second Opinions in Breast Cancer Diagnostics and Treatment: A Retrospective Analysis

E. Heeg, Y. A. Civil, M. A. Hillen, C. H. Smorenburg, L. A. E. Woerdeman, E. J. Groen, H. A. O. Winter-Warnars, M. T. F. D. Vrancken Peeters
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Challenges in Clinical Trial Implementation: Results from a Survey of the National Accreditation Program of Breast Centers (NAPBC)

Anna Weiss MD, Nicole E. Lopez MD, Erin P. Ward MD, Katherine C. Lee MD, Abigail S. Caudle MD, Diana Dickson-Witmer MD, Cecilia Chang MS, Kaitlyn Kelly MD, Linda Williams Martin MD, MPH, Lisa Kay Jacobs MD, Kelly K. Hunt MD, Katherine Yao MD, Sarah L. Blair MD
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An In-Visit Decision Aid for Surgeons to Address Decision Making for Bilateral Mastectomy for Newly Diagnosed Breast Cancer Patients

Katharine Yao MD, Jeff Belkora PhD, Clara Lee MD, Kristine Kuchta MS, Catherine Pesce MD, Katherine Kopkash MD, Sarah Rabbitt RN, Ermilo Barrera MD, Sandra Simovic BS, Karen Sepucha PhD
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Heterogeneous Responses of Axillary Lymph Node Metastases to Neoadjuvant Chemotherapy are Common and Depend on Breast Cancer Subtype

Antonia Glaeser, Hans-Peter Sinn MD, Carlos Garcia-Etienne MD, Fabian Riedel MD, Sarah Hug MD, Benedikt Schaefgen MD, Michael Golatta PhD, Andre Hennigs PhD, Manuel Feisst, Christof Sohn PhD, Joerg Heil PhD
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Colorectal Cancer

Safety of Single-Site Laparoscopic Surgery Requiring Perioperative Heparinization in Colorectal Cancer: Propensity Score-Matched Analysis

Kazuya Iwamoto MD, Hidekazu Takahashi MD, Makoto Fujii MD, Naotsugu Haraguchi MD, Taishi Hata MD, Chu Matsuda MD, Hirofumi Yamamoto MD, Tsunekazu Mizushima MD, Masaki Mori MD, Doki Yuichiro MD
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The Relationship Between Tumor Budding, Tumor Microenvironment, and Survival in Patients with Primary Operable Colorectal Cancer

Hester C. van Wyk PhD, Antonia Roseweir PhD, Peter Alexander MBChB, James H. Park PhD, Paul G. Horgan PhD, Donald C. McMillan PhD, Joanne Edwards PhD
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Endocrine Tumors

Levothyroxine Supplementation Following Hemithyroidectomy: Incidence, Risk Factors, and Characteristics

Dongbin Ahn MD, Gil Joon Lee MD, Jin Ho Sohn MD, PhD
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Comparing the Utility and Surgical Outcomes of Harmonic Focus Ultrasonic Scalpel with Ligasure Small Jaw Bipolar Device in Thyroidectomies: A Prospective Randomized Controlled Trial

Shen-Han Lee MA, MBBS, PhD, MRCS, Thien Khanh Nguyen MD, MRCS, Whee-Sze Ong MAppStats, Benjamin Haaland PhD, Gerald Ci-An Tay MBBS, FRCS, Ngian Chye Tan MBBS, FRCS, Hiang Khoon Tan MBBS, PhD, FRCS, Jeremy Chung Fai Ng MBBS, FRCS, N. Gopalakrishna Iyer MBBS, PhD, FRCS
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Long-Term Oncologic Outcomes After Curative Resection of Familial Medullary Thyroid Carcinoma

Philip M. Spanheimer MD, Ian Ganly MD, PhD, Joanne Chou MS, Marinela Capanu PhD, Ronald A. Ghossein MD, R. Michael Tuttle MD, Richard J. Wong MD, Ashok R. Shaha MD, Brian R. Untch MD
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A Novel N Staging System for Predicting Survival in Patients with Medullary Thyroid Cancer

Lili Chen MM, Kai Qian MD, Kai Guo MM, Xiaoke Zheng MM, Wenyu Sun MM, Tuanqi Sun MD, Yunjun Wang MD, Duanshu Li MM, Yi Wu MD, Qinghai Ji MD, Zhuoying Wang MD, PhD
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Preoperative Computed Tomography Changes Surgical Management for Clinically Low-Risk Well-Differentiated Thyroid Cancer

Pim J. Bongers MD, Raoul Verzijl MD, Michael Dzingala BSc, Menno R. Vriens MD, PhD, Eugene Yu MD, Jesse D. Pasternak MD, MPH, FRCSC, Lorne E. Rotstein MD, FACS, FRCSC
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Gastrointestinal Oncology

Comparison of Tissue and Blood Concentrations of Oxaliplatin Administrated by Different Modalities of Intraperitoneal Chemotherapy

Urs Giger-Pabst MD, Petru Bucur MD, PhD, Sébastien Roger PhD, Thomas Albert Falkenstein MD, Nicolas Tabchouri MD, Alain Le Pape PhD, Stéphanie Lerondel PhD, Cédric Demtröder MD, Ephrem Salamé MD, PhD, Mehdi Ouaissi MD, PhD
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Curative-Intent Surgery for Stage IV Advanced Gastric Cancer: Who Can Undergo Surgery and What Are the Prognostic Factors for Long-Term Survival?

Sho Sato MD, PhD, Chikara Kunisaki MD, PhD, Yusaku Tanaka, Kei Sato MD, PhD, Hiroshi Miyamoto MD, PhD, Norio Yukawa MD, PhD, Takashi Kosaka MD, PhD, Hirotoshi Akiyama MD, PhD, Itaru Endo MD, PhD, Toshihiro Misumi PhD
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Laparoscopic Distal Pancreatectomy for Left-Sided Pancreatic Cancer Using the “Caudo-Dorsal Artery First Approach”

Yusuke Ome MD, Yasuji Seyama MD, Manami Doi MD, Jun Muto MD
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Head and Neck Oncology

The Clinical Significance of Strap Muscle Invasion in Papillary Thyroid Cancer on Local Recurrence: Is Less Surgery Warranted?

Hunter J. Underwood MD, Kepal N. Patel MD
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Clinical Significance of Gross Invasion of Strap Muscles in Patients With 1- to 4-cm-Sized Papillary Thyroid Carcinoma Undergoing Lobectomy

Eyun Song MD, Won Woong Kim MD, Min Ji Jeon MD, PhD, Tae-Yon Sung MD, PhD, Dong Eun Song MD, PhD, Tae Yong Kim MD, PhD, Ki Wook Chung MD, PhD, Won Bae Kim MD, PhD, Young Kee Shong MD, PhD, Suck Joon Hong MD, PhD, Yu-Mi Lee MD, PhD, Won Gu Kim MD, PhD
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The First Human Trial of Transoral Robotic Surgery Using a Single-Port Robotic System in the Treatment of Laryngo-Pharyngeal Cancer

Young Min Park MD, PhD, Da Hee Kim MD, Min Seok Kang MD, Jae Yol Lim MD, PhD, Eun Chang Choi MD, PhD, Yoon Woo Koh MD, PhD, Se-Heon Kim MD, PhD
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Sentinel Node Biopsy in 105 High-Risk Cutaneous SCCs of the Head and Neck: Results of a Multicenter Prospective Study

Craig P. Mooney BSc, MBBS, Richard C. W. Martin MBChB, ChM, FRACS, Richard Dirven MD, PhD, Bruce G. Ashford FRACDS, FRACS, Kerwin Shannon MBBS, FRACS, Carsten E. Palme MBBS, FRACS, Quan Ngo MBBS (Hons), MS, FRACS, James Wykes MBBS, FRACS, Sarah Davies RN, BSc, Kan Gao BEng, Sydney Ch’ng MBBS, PhD, FRACS, Tsu-Hui Low MBBS (Hons), FRACS, Ruta Gupta MBBS, FRCPA, Jonathan R. Clark MBiostats, FRACS
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Health Services Research and Global Oncology

2019 SSO Presidential Address: Serendipity and Strategy on the Path of Progress

Armando E. Giuliano MD
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Economic Analysis of Adjuvant Chemoradiotherapy Compared with Chemotherapy in Resected Pancreas Cancer

Nivethan Vela MSc, Laura E. Davis MSc, Stephanie Y. Cheng MSc, Ahmed Hammad MD, Ying Liu MSc, Daniel J. Kagedan MD, MSc, Lawrence Paszat MD, MS, Lev D. Bubis MD, MHS, MSc, Craig C. Earle MD, MSc, Sten Myrehaug MD, Alyson L. Mahar PhD, Nicole Mittmann PhD, Natalie G. Coburn MD, MPH
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Deficits in the Palliative Care Process Measures in Patients with Advanced Pancreatic Cancer Undergoing Operative and Invasive Nonoperative Palliative Procedures

Brooks V. Udelsman MD, MHS, Elizabeth J. Lilley MD, MPH, Motaz Qadan PhD, David C. Chang PhD, MBA, MPH, Keith D. Lillemoe MD, Charlotta Lindvall MD, PhD, Zara Cooper MD, MSc
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Comparative Age-Based Prospective Multi-Institutional Observations of 12,367 Patients Enrolled to the American College of Surgeons Oncology Group (ACOSOG) Z901101 Trials (Alliance)

Waddah B. Al-Refaie MD, Paul A. Decker MS, Karla V. Ballman PhD, Peter W. T. Pisters MD, Mitchell C. Posner MD, Kelly K. Hunt MD, Bryan Meyers MD, Armin D. Weinberg PhD, Heidi Nelson MD, Lisa Newman MD, Angelina Tan MD, Jennifer G. Le-Rademacher PhD, Arti Hurria MD, Aminah Jatoi MD
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Malignant Peritoneal Mesothelioma: Patterns of Care and Survival in the Netherlands: A Population-Based Study

Nadine L. de Boer MD, Job P. van Kooten MD, Ronald A. M. Damhuis MD, PhD, Joachim G. J. V. Aerts MD, PhD, Cornelis Verhoef MD, PhD, Eva V. E. Madsen MD, PhD
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Risk of Dementia in Gastric Cancer Survivors Who Underwent Gastrectomy: A Nationwide Study in Korea

Yoon Jin Choi MD, PhD, Dong Wook Shin MD, Dr PH, MBA, Wooyoung Jang MD, Dong Ho Lee MD, PhD, Su-Min Jeong MD, Sanghyun Park MS, Kyung-do Han PhD, Yong Gyu Park PhD
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Hepatobiliary Tumors

Radiomics: A Well-Intentioned Leap of Faith

Clifford S. Cho MD
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Preoperative Radiomic Approach to Evaluate Tumor-Infiltrating CD8+ T Cells in Hepatocellular Carcinoma Patients Using Contrast-Enhanced Computed Tomography

Haotian Liao MD, Zhen Zhang MD, Jie Chen MD, Mingheng Liao MD, PhD, Lin Xu MD, Zhenru Wu MD, Kefei Yuan PhD, Bin Song MD, PhD, Yong Zeng MD, PhD
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Severe Preoperative Symptoms Delay Readiness to Return to Intended Oncologic Therapy (RIOT) After Liver Resection

Heather A. Lillemoe MD, Rebecca K. Marcus MD, Bradford J. Kim MD, MHS, Nisha Narula MD, Catherine H. Davis MD, MPH, Qiuling Shi PhD, Xin Shelley Wang MD, MPH, Thomas A. Aloia MD, FACS
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Prognostic Relevance of a Complete Pathologic Response in Liver Transplantation for Hepatocellular Carcinoma

Michał Grąt MD, PhD, Marek Krawczyk MD, PhD, Jan Stypułkowski MD, Marcin Morawski MD, Maciej Krasnodębski MD, PhD, Michał Wasilewicz MD, PhD, Zbigniew Lewandowski PhD, Karolina Grąt MD, Waldemar Patkowski MD, PhD, Krzysztof Zieniewicz MD, PhD
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The Achievement of a Sustained Virological Response Either Before or After Hepatectomy Improves the Prognosis of Patients with Primary Hepatitis C Virus-Related Hepatocellular Carcinoma

Yukiyasu Okamura MD, Teiichi Sugiura MD, Takaaki Ito MD, Yusuke Yamamoto MD, Ryo Ashida MD, Katsuhisa Ohgi MD, Katsuhiko Uesaka MD
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Laparoscopic Parenchymal-Sparing Hepatectomy for Multiple Colorectal Liver Metastases Improves Outcomes and Salvageability: A Propensity Score-Matched Analysis

Shinya Okumura MD, PhD, Nicolas Tabchouri MD, Universe Leung MD, Pascale Tinguely MD, Christophe Louvet MD, PhD, Marc Beaussier MD, PhD, Brice Gayet MD, PhD, David Fuks MD, PhD
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Prediction of Histopathologic Growth Patterns of Colorectal Liver Metastases with a Noninvasive Imaging Method

Jin Cheng MD, Jingwei Wei PhD, Tong Tong MD, Weiqi Sheng MD, Yinli Zhang MD, Yuqi Han PhD, Dongsheng Gu PhD, Nan Hong MD, Yingjiang Ye MD, Jie Tian PhD, Yi Wang MD
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Adjuvant Hepatic Arterial Infusion Pump Chemotherapy After Resection of Colorectal Liver Metastases: Results of a Safety and Feasibility Study in The Netherlands

Florian E. Buisman MD, Dirk J. Grünhagen MD, PhD, Marjolein Y. V. Homs MD, PhD, Cecile Grootscholten MD, PhD, Wills F. Filipe MD, Nancy E. Kemeny MD, Andrea Cercek MD, Micheal I. D’Angelica MD, Maarten L. Donswijk MD, Leni van Doorn NP, Jasper Emmering MD, PhD, William R. Jarnagin MD, T. Peter Kingham MD, Elisabeth G. Klompenhouwer MD, PhD, Niels F. M. Kok MD, PhD, Maria C. Kuiper NP, Adriaan Moel
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Pure Laparoscopic Anatomic Resection of the Segment 8 Ventral Area Using the Transfissural Glissonean Approach

Ji Hoon Kim MD, Hyeyoung Kim PhD, MD
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Melanoma

A Call to Arms: Surgeons Must Play an Important and Early Role in the Management of Patients with Advanced Melanoma

Michael C. Lowe MD, Keith A. Delman MD
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Impact of Effective Systemic Therapy on Metastasectomy in Stage IV Melanoma: A Matched-Pair Analysis

Daniel W. Nelson DO, Trevan D. Fischer MD, Amanda N. Graff-Baker MD, Ahmed Dehal MD, Stacey Stern MS, Anton J. Bilchik MD, Mark B. Faries MD
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Survival Outcomes of Patients with Clinical Stage III Melanoma in the Era of Novel Systemic Therapies

Yun Song MD, Andrew D. Tieniber MD, Phyllis A. Gimotty PhD, Tara C. Mitchell MD, Ravi K. Amaravadi MD, Lynn M. Schuchter MD, Douglas L. Fraker MD, Giorgos C. Karakousis MD
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Efficacy of Talimogene Laherparepvec (T-VEC) Therapy in Patients with In-Transit Melanoma Metastasis Decreases with Increasing Lesion Size

Sabran J. Masoud BS, Janice B. Hu BA, MSc, Georgia M. Beasley MD, MHSc, John H. Stewart IV MD, MBA, Paul J. Mosca MD, PhD, MBA
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Squamous Cell Carcinoma with Regional Metastasis to Axilla or Groin Lymph Nodes: a Multicenter Outcome Analysis

George Pang MD, Nicole J. Look Hong MD, MSc, Gabrielle Paull MSc, Johanna Dobransky MHK, BSc, CCRP, Suzana Kupper MD, Scott Hurton MD, Daniel J. Kagedan MD, May Lynn Quan MD, Lucy Helyer MD, MSc, Carolyn Nessim MD, MSc, Frances C. Wright MD, Med
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Practice Patterns and Prognostic Value of Sentinel Lymph Node Biopsy for Thick Melanoma: A National Cancer Database Study

Yun Song MD, Feredun S. Azari MD, Daniel Aryeh Metzger BA, Douglas L. Fraker MD, Giorgos C. Karakousis MD
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Inguinal and Ilio-inguinal Lymphadenectomy in Management of Palpable Melanoma Lymph Node Metastasis: A Long-Term Prospective Evaluation of Morbidity and Quality of Life

Michael A. Henderson MD, FRACS, D. Gyorki MD, FRACS, B. H. Burmeister MD, FRANZCR, J. Ainslie MBBS, FRANZCR, R. Fisher PhD, J. Di Iulio PhD, B. M. Smithers MBBS, FRACS, A. Hong MBBS, PhD, FRANZCR, K. Shannon MBBS, FRACS, R. A. Scolyer MD, FRCPA, S. Carruthers MBBS, FRANZCR, B. J. Coventry MBBS, PhD, FRACS, S. Babington MBBS, FRANZCR, J. Duprat MD, PhD, H. J. Hoekstra MD, J. F. Thompson MD, FRACS
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The Prognosis and Natural History of In-Transit Melanoma Metastases at a High-Volume Centre

Emilia Nan Tie MD, Lumine H. Na MS, Rodney J. Hicks MD, FRACP, FAHMS, John Spillane MBBS, FRACS, David Speakman MBBS, FRACS, Michael A. Henderson MBBS, MD, FRACS, David E. Gyorki MBBS, MD, FRACS
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Pancreatic Tumors

Radiotherapy as an Adjunct to Surgery for Pancreatic Cancer: Where Are We After More Than 30 Years of Research and Trials?

Anthony Ferrantella MD, Vikas Dudeja MD, Chandrakanth Are MD, MBA
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Perioperative Clinical Trials for Pancreatic Cancer in the National Clinical Trials Network

Matthew H. G. Katz MD, FACS
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Editorial About: “A Prospective, Open-Label, Multicenter Phase II Trial of Neoadjuvant Therapy Using Full-Dose Gemcitabine and S-1 Concurrent with Radiation for Resectable Pancreatic Ductal Adenocarcinoma”

Patrick B. Schwartz MD, Nataliya V. Uboha MD, PhD, Sharon M. Weber MD
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Perioperative Gemcitabine + Erlotinib Plus Pancreaticoduodenectomy for Resectable Pancreatic Adenocarcinoma: ACOSOG Z5041 (Alliance) Phase II Trial

Alice C. Wei MD, Fang-Shu Ou PhD, Qian Shi PhD, Xiomara Carrero BS, Eileen M. O’Reilly MD, Jeffrey Meyerhardt MD, Robert A. Wolff MD, Hedy L. Kindler MD, Douglas B. Evans MD, Vikram Deshpande MBBS, Joseph Misdraji MD, Eric Tamm MD, Dushyant Sahani MD, Malcolm Moore MD, Elliot Newman MD, Nipun Merchant MD, Jordan Berlin MD, Laura W. Goff MD, Peter Pisters MD, Mitchell C. Posner MD
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A Prospective, Open-Label, Multicenter Phase 2 Trial of Neoadjuvant Therapy Using Full-Dose Gemcitabine and S-1 Concurrent with Radiation for Resectable Pancreatic Ductal Adenocarcinoma

Hidetoshi Eguchi MD, Yutaka Takeda MD, Hidenori Takahashi MD, Shin Nakahira MD, Masaki Kashiwazaki MD, Junzo Shimizu MD, Daisuke Sakai MD, Fumiaki Isohashi MD, Hiroaki Nagano MD, Masaki Mori MD, Yuichiro Doki MD
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MiR-194-5p in Pancreatic Ductal Adenocarcinoma Peritoneal Washings is Associated with Peritoneal Recurrence and Overall Survival in Peritoneal Cytology-Negative Patients

Hirokazu Kubo MD, Yukihiko Hiroshima MD, PhD, Ryutaro Mori MD, PhD, Yusuke Saigusa PhD, Takashi Murakami MD, PhD, Yasuhiro Yabushita MD, PhD, Yu Sawada MD, PhD, Yuki Homma MD, PhD, Takafumi Kumamoto MD, PhD, Ryusei Matsuyama MD, PhD, Itaru Endo MD, PhD
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Management of Acute Cholecystitis during Neoadjuvant Therapy in Patients with Pancreatic Adenocarcinoma

Neil R. Jariwalla BS, Abdul H. Khan MD, Kulwinder Dua MD, Kathleen K. Christians MD, Callisia N. Clarke MD, MS, Mohammed Aldakkak MD, Ben George MD, Sean Tutton MD, William Rilling MD, Beth Erickson MD, Douglas B. Evans MD, Susan Tsai MD, MHS
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Accuracy of Fukuoka and American Gastroenterological Association Guidelines for Predicting Advanced Neoplasia in Pancreatic Cyst Neoplasm: A Meta-Analysis

Jiayuan Wu MD, Yufeng Wang MM, Zitao Li MM, Huilai Miao MD
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Reconstructive Oncology

Postoperative Cancer Surveillance Following Oncoplastic Surgery with Latissimus Dorsi Flap: a Matched Case–Control Study

Kenneth L. Fan MD, Simon Yang MD, Seho Park MD, PhD, Tae Hwan Park MD, PhD, Seung Yong Song MD, PhD, Nara Lee MD, Dae Hyun Lew MD, PhD, Min Jung Kim MD, PhD, Dong Won Lee MD, PhD
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Sarcoma

To Biopsy, or Not to Biopsy: Is There Really a Question?

Mark Fairweather MD, Chandrajit P. Raut MSc
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If Active Surveillance is the Standard of Care for Desmoid Patients, When Should Intervention be Considered?

Rebecca A. Gladdy MD, PhD, FRCSC, FACS, Abha A. Gupta MD, MSc, FRCPC
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Early and Late Complications of Percutaneous Core Needle Biopsy of Retroperitoneal Tumors at Two Tertiary Sarcoma Centers

David Berger-Richardson MD, Sally M. Burtenshaw MSc, Andrea M. Ibrahim MSc, Rebecca A. Gladdy MD, Rebecca Auer MD, Rob Beecroft MD, Brendan C. Dickson MD, Bibianna Purgina MD, Kristin Ambacher MD, Carolyn Nessim MD, Carol J. Swallow MD
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Outcome of Primary Desmoid Tumors at All Anatomic Locations Initially Managed with Active Surveillance

Winan J. van Houdt MD, PhD, MSc, Olga Husson PhD, Alisha Patel, Robin L. Jones MD, Myles J. F. Smith MB, BCh, BAO, PhD, FRCSI, Aisha B. Miah MD, PhD, Christina Messiou MD, Eleonor Moskovic MD, Omar Al-Muderis, Charlotte Benson MD, Shane Zaidi MD PhD, Alison Dunlop, Dirk C. Strauss MD, Andrew J. Hayes MD, PhD, Winette T. A. van der Graaf MD, PhD
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Functional Outcome Measurement in Patients with Lower-Extremity Soft Tissue Sarcoma: A Systematic Literature Review

Gilber Kask MD, Ian Barner-Rasmussen PhD, Jussi Petteri Repo MD, PhD, Magnus Kjäldman MD, Kaarel Kilk MD, Carl Blomqvist PhD, Erkki Juhani Tukiainen MD, PhD
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The Prognostic Value of Lymphovascular Invasion in Truncal and Extremity Soft Tissue Sarcomas: An Analysis from the National Cancer Database

Cecilia G. Ethun MD, Alexandra G. Lopez-Aguiar MD, Jeffery M. Switchenko PhD, Theresa W. Gillespie PhD, Keith A. Delman MD, Charles A. Staley MD, Shishir K. Maithel MD, Kenneth Cardona MD
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Is Peritoneal Tumor Penetration of Prognostic Importance in Gastrointestinal Stromal Tumors?

T. Hølmebakk MD, B. Bjerkehagen MD, PhD, I. V. K. Lobmaier MD, I. Hompland MD, PhD, S. Stoldt MD, K. Boye MD, PhD
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Thoracic Oncology

Clinical Implications of Conversion Surgery After Induction Therapy for T4b Thoracic Esophageal Squamous Cell Carcinoma

Hiroshi Miyata MD, Keijirou Sugimura MD, Masaaki Motoori MD, Takeshi Omori MD, Kazuyoshi Yamamoto MD, Yoshitomo Yanagimoto MD, Naoki Shinno MD, Masayoshi Yasui MD, Hidenori Takahashi MD, Hiroshi Wada MD, Masayuki Ohue MD, Masahiko Yano MD
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The Influence of the Perioperative Nutritional Status on the Survival Outcomes for Esophageal Cancer Patients with Neoadjuvant Chemotherapy

Makoto Hikage MD, PhD, Yusuke Taniyama MD, PhD, Tadashi Sakurai MD, PhD, Chiaki Sato MD, PhD, Kai Takaya MD, PhD, Hiroshi Okamoto MD, PhD, Takuro Konno MD, PhD, Naoto Ujiie MD, PhD, Takeshi Naitoh MD, PhD, Michiaki Unno MD, PhD, Takashi Kamei MD, PhD
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Dysphagia Score as a Predictor of Adverse Events Due to Triplet Chemotherapy and Oncological Outcomes in 434 Consecutive Patients with Esophageal Cancer

Takaomi Hagi MD, Tomoki Makino MD, PhD, Makoto Yamasaki MD, PhD, Koji Tanaka MD, PhD, Naohiro Nishida MD, PhD, Daisuke Sakai MD, PhD, Masaaki Motoori MD, PhD, Yutaka Kimura MD, PhD, Taroh Satoh MD, PhD, Masaki Mori MD, PhD, Yuichiro Doki MD, PhD
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Quality of Life During and After Completion of Neoadjuvant Chemoradiotherapy for Esophageal and Junctional Cancer

B. J. Noordman MD, PhD, M. G. E. Verdam PhD, B. Onstenk MD, MSc, J. Heisterkamp MD, PhD, W. J. B. M. Jansen MSc, I. S. Martijnse MD, PhD, S. M. Lagarde MD, PhD, B. P. L. Wijnhoven MD, PhD, C. M. M. Acosta BSc, A. van der Gaast MD, PhD, M. A. G. Sprangers MD, PhD, J. J. B. van Lanschot MD, PhD
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Modified Systemic Inflammation Score is Useful for Risk Stratification After Radical Resection of Squamous Cell Carcinoma of the Esophagus

Mitsuro Kanda MD, FACS, Masahiko Koike MD, Chie Tanaka MD, Daisuke Kobayashi MD, Norifumi Hattori MD, Masamichi Hayashi MD, FACS, Suguru Yamada MD, FACS, Kenji Omae MD, Michitaka Fujiwara MD, Yasuhiro Kodera MD, FACS
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Translational Research and Biomarkers

Editorial: A Novel Monoclonal Antibody-Targeting Angiogenesis by Inhibiting Secreted Frizzled-Related Protein 2

Julie E. Lang MD, FACS, William W. Tseng MD, Irene Kang MD
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Identification, Friend or Foe: Vimentin and α-Smooth Muscle Actin in Cancer-Associated Fibroblasts

Sachiyo Nomura MD, PhD, AGAF, FACS
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Development of a Novel Humanized Monoclonal Antibody to Secreted Frizzled-Related Protein-2 That Inhibits Triple-Negative Breast Cancer and Angiosarcoma Growth In Vivo

Denise Garcia MD, Patrick Nasarre PhD, Ingrid V. Bonilla BS, Eleanor Hilliard BS, Yuri K. Peterson PhD, Laura Spruill MD, PhD, Anne-Marie Broome PhD, Elizabeth G. Hill PhD, Jason T. Yustein MD, PhD, Shikhar Mehrotra PhD, Nancy Klauber-DeMore MD, FACS
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Vimentin Expression in Tumor Microenvironment Predicts Survival in Pancreatic Ductal Adenocarcinoma: Heterogeneity in Fibroblast Population

Hiromitsu Maehira MD, Toru Miyake MD, PhD, Hiroya Iida MD, PhD, Aya Tokuda MD, Haruki Mori MD, Daiki Yasukawa MD, Ken-ichi Mukaisho MD, PhD, Tomoharu Shimizu MD, PhD, Masaji Tani MD, PhD
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Association Between Preoperative Muscle Mass and Intraoperative Bacterial Translocation in Patients Undergoing Hepatectomy, Pancreatoduodenectomy, and Esophagectomy

Kumiko Akashi MD, Yukihiro Yokoyama MD, Takashi Mizuno MD, Tetsuya Abe MD, Masahide Fukaya MD, Takashi Asahara PhD, Masato Nagino MD
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Comprehensive Exploration to Identify Predictive DNA Markers of ΔNp63/SOX2 in Drug Resistance in Human Esophageal Squamous Cell Carcinoma

Yosuke Ooizumi MD, Keita Kojima MD, Kazuharu Igarashi MD, Yoko Tanaka MD, Hiroki Harada MD, Kazuko Yokota MD, Takeshi Kaida MD, Satoru Ishii MD, PhD, Toshimichi Tanaka MD, PhD, Keigo Yokoi MD, PhD, Nobuyuki Nishizawa MD, PhD, Marie Washio MD, Hideki Ushiku MD, PhD, Hiroshi Katoh MD, PhD, Yoshimasa Kosaka MD, PhD, Hiroaki Mieno MD, PhD, Kei Hosoda MD, PhD, Masahiko Watanabe MD, PhD, FACS, Chikatosh
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WiNTRLINC1/ASCL2/c-Myc Axis Characteristics of Colon Cancer with Differentiated Histology at Young Onset and Essential for Cell Viability

Kazuko Yokota MD, Yoko Tanaka MD, Hiroki Harada MD, Takeshi Kaida MD, Syuji Nakamoto MD, Takafumi Soeno MD, Yoshiki Fujiyama MD, Mitsuo Yokota MD, Ken Kojo MD, PhD, Hirohisa Miura MD, Takahiro Yamanashi MD, Takeo Sato MD, PhD, Takatoshi Nakamura MD, PhD, Masahiko Watanabe MD, PhD, FACS, Keishi Yamashita MD, PhD, FACS
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Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases

Malin Enblad MD, PhD, Wilhelm Graf MD, PhD, Alexei Terman MD, PhD, Pascal Pucholt PhD, Björn Viklund, Anders Isaksson PhD, Helgi Birgisson MD, PhD
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